SCHEMBL40564

SCHEMBL40564

CCCCC(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.75
ESR1 P03372 6/20 0.75
SMN1; SMN2 Q16637 5/20 0.75
ADORA3 P0DMS8 3/20 0.75
ATM Q13315 3/20 0.75
PGR P06401 3/20 0.75
AR P10275 3/20 0.75
CHRM1 P11229 2/20 0.75
TBXA2R P21731 2/20 0.75
SLC6A3 Q01959 2/20 0.75
ADRA1A P35348 1/20 0.75
OPRM1 P35372 1/20 0.75
KMT2A Q03164 5/20 0.69
NR3C1 P04150 2/20 0.69
SHBG P04278 2/20 0.69
SLC6A4 P31645 2/20 0.69
HTR2B P41595 2/20 0.69
FYN P06241 1/20 0.69
ADRA2C P18825 1/20 0.69
SLC6A2 P23975 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4333126 1.00 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL11102416 1.00 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL547938 0.96 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL17419453 0.96 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL548012 0.96 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL1315380 0.96 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL17419466 0.96 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL9404736 0.95 LMNA (0.77) LMNAESR1SMN1; SMN2ADORA3ATM
Estradiol Acetate SCHEMBL547226 0.93 LMNA (0.80) LMNAESR1SMN1; SMN2ADORA3ATM
Estradiol Dipropionate SCHEMBL11698942 0.92 MAPT (0.82) LMNAESR1SMN1; SMN2ADORA3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7276 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-20260027215-A1 COMPOSITIONS FOR TRANSPORT OF THERAPEUTIC CARGOS USING BINDERS TARGETING CA-IV RECEPTIVE BIO INC (US) 2026-01-29 US claimed
EP-4608425-A1 METHODS OF TREATING ESTROGEN SENSITIVE DISEASES WITH CANNABIS EXTRACT Ecofibre USA Inc. (US) 2025-09-03 EP claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
US-12364682-B2 Use of tegaserod in preparation of anti-tumor drug QINGDAO HAIJI BIOMEDICINE CO., LTD. (CN) 2025-07-22 US claimed
CN-120131073-A Clinical pregnancy prediction method after frozen embryo transplantation based on ultrasonic radiology group 安徽医科大学第一附属医院 2025-06-13 CN claimed
US-20250191770-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2025-06-12 US claimed
US-12310928-B2 Enthesis healing UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-05-27 US claimed
CN-119857071-A High-efficiency external medicine for repairing leukoplakia vulvae and preparation method thereof 韩志君 2025-04-22 CN claimed
EP-4531594-A1 PREVENTION OF ESTRUS IN SOW AND RUMINANTS Insigna Inc. (US) 2025-04-09 EP claimed
EP-0256668-A2 Method for treating male sexual dysfunction UNIVERSITY OF FLORIDA (US) 1988-02-24 EP claimed
WO-1987007138-A1 TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS AND PROCESS FOR ADMINISTRATION RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 1987-12-03 WO claimed
EP-0220844-A2 Use of estrogen-dihydropyridine compounds for weight control UNIVERSITY OF FLORIDA (US) 1987-05-06 EP claimed
US-4617298-A STEROIDS UNIVERSITY OF FLORIDA (US) 1986-10-14 US claimed
EP-0136011-A2 A method of hormonal treatment of peri-menopausal, menopausal and post-menopausal disorders and multi-preparation pack therefor PRE JAY HOLDINGS LTD. (CA) 1985-04-03 EP claimed
US-4438139-A MADE OF POLYVINYL ALCOHOL AND POLYVINYL PYRROLIDONE, SUSTAINED RELEASE KEY PHARMACEUTICALS, INC. (US) 1984-03-20 US claimed
US-4330538-A Use of estradiol valerate as an anti-depressant SCHERING AKTIENGESELLSCHAFT (DE) 1982-05-18 US claimed
US-4321252-A Polymeric diffusion matrix containing ester derivatives of estradiol KEY PHARMACEUTICALS, INC. (US) 1982-03-23 US claimed
US-4145416-A ESTRADIOL AND ESTRIOL DERIVATIVES SCHERING, A.G. (DE) 1979-03-20 US claimed
US-4076811-A MENOPAUSE, ESTRADIOL ESTROGEN SCHERING AKTIENGESELLSCHAFT (DT) 1978-02-28 US claimed