Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.75 |
| ▸ | ESR1 | P03372 | 6/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.75 |
| ▸ | ATM | Q13315 | 3/20 | 0.75 |
| ▸ | PGR | P06401 | 3/20 | 0.75 |
| ▸ | AR | P10275 | 3/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.69 |
| ▸ | SHBG | P04278 | 2/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.69 |
| ▸ | HTR2B | P41595 | 2/20 | 0.69 |
| ▸ | FYN | P06241 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333126 | 1.00 | LMNA (0.75) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL40564 | 1.00 | LMNA (0.75) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL547938 | 0.96 | LMNA (0.73) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL17419453 | 0.96 | LMNA (0.73) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL548012 | 0.96 | LMNA (0.73) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL1315380 | 0.96 | LMNA (0.73) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL17419466 | 0.96 | LMNA (0.73) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| SCHEMBL9404736 | 0.95 | LMNA (0.77) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| Estradiol Acetate SCHEMBL547226 | 0.93 | LMNA (0.80) | LMNAESR1SMN1; SMN2ADORA3ATM | |
| Estradiol Dipropionate SCHEMBL11698942 | 0.92 | MAPT (0.82) | LMNAESR1SMN1; SMN2ADORA3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438139-A | MADE OF POLYVINYL ALCOHOL AND POLYVINYL PYRROLIDONE, SUSTAINED RELEASE | KEY PHARMACEUTICALS, INC. (US) | 1984-03-20 | — | — | US | claimed |
| US-4321252-A | Polymeric diffusion matrix containing ester derivatives of estradiol | KEY PHARMACEUTICALS, INC. (US) | 1982-03-23 | — | — | US | claimed |
| US-20240115490-A1 | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF | LUPIN, INC. | 2024-04-11 | — | — | US | disclosed |
| CN-117720605-A | beta-Estradiol small molecule sandwich ELISA detection kit and preparation method thereof | 伊莱瑞特(武汉)生物技术有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024030116-A1 | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF | Lupin Inc. (US) | 2024-02-08 | — | — | WO | disclosed |
| US-20230404911-A1 | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF | LUPIN INC | 2023-12-21 | — | — | US | disclosed |
| US-11389537-B2 | Drug delivery system for sustained delivery of bioactive agents | UPM-KYMMENE CORPORATION (FI) | 2022-07-19 | — | — | US | disclosed |
| EP-3893884-A1 | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF | Lupin Inc. (US) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020123148-A1 | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF | Lupin Inc. (US) | 2020-06-18 | — | — | WO | disclosed |
| US-20200179274-A1 | DRUG DELIVERY SYSTEM FOR ULTRA-LOW DOSE ESTROGEN COMBINATIONS AND METHODS AND USES THEREOF | Lupin Inc. (US) | 2020-06-11 | — | — | US | disclosed |
| US-20140322327-A1 | DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS | UPM-KYMMENE CORPORATION (FI) | 2014-10-30 | — | — | US | disclosed |
| US-4438139-A | MADE OF POLYVINYL ALCOHOL AND POLYVINYL PYRROLIDONE, SUSTAINED RELEASE | KEY PHARMACEUTICALS, INC. (US) | 1984-03-20 | — | — | US | disclosed |
| US-4321252-A | Polymeric diffusion matrix containing ester derivatives of estradiol | KEY PHARMACEUTICALS, INC. (US) | 1982-03-23 | — | — | US | disclosed |
| US-4286587-A | Vaginal drug delivery system made from polymer | ALZA CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4250611-A | Process for making drug delivery device with reservoir | ALZA CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4237885-A | Delivery system with mated members for storing and releasing a plurality of beneficial agents | ALZA CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| US-4215691-A | Vaginal contraceptive system made from block copolymer | ALZA CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |