Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198931 | 0.82 | ALDH1A1 (0.39) | MAPK1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL6623185 | 0.81 | MEN1 (0.61) | MAPK1ALDH1A1GPR35TP53HPGD | |
| SCHEMBL32674534 | 0.81 | MEN1 (0.61) | MAPK1ALDH1A1GPR35TP53HPGD | |
| SCHEMBL2748087 | 0.78 | NPC1 (0.53) | MAPK1ALDH1A1GPR35TP53HPGD | |
| SCHEMBL4845107 | 0.78 | GPR35 (0.39) | ALDH1A1GPR35HPGDHSD17B10KDM4E | |
| SCHEMBL3754199 | 0.77 | MEN1 (0.59) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL5006964 | 0.75 | NPC1 (0.50) | MAPK1ALDH1A1GPR35TP53HPGD | |
| SCHEMBL1238135 | 0.73 | ESR1 (0.50) | TP53SMN1; SMN2L3MBTL1MAPTLMNA | |
| SCHEMBL2710599 | 0.73 | GAA (0.42) | MAPK1ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL31030078 | 0.73 | ESR1 (0.50) | TP53SMN1; SMN2L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423180-B2 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-09 | — | — | US | disclosed |
| US-7423180-B2 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-09 | — | — | US | disclosed |
| US-7423180-B2 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2008-09-09 | — | — | US | disclosed |
| US-20060161016-A1 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1602641-A1 | BIS(3-AMINO-4-HYDROXYPHENYL)ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161016-A1 | Bis(3-amino-4-hydroxyphenyl)adamantane derivatives and process for production thereof | HTR3D, ALKBH3, ALKBH5 | MAPK1 1645/4885ALDH1A1 768/4885GPR35 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.