Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AKT2 | P31751 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586818 | 0.89 | KMT2A (0.39) | PTGS1PTGS2KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4586736 | 0.89 | ALDH1A1 (0.45) | PTGS1PTGS2TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL4586151 | 0.87 | ALDH1A1 (0.53) | PTGS2TDP1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4587361 | 0.84 | PTGS2 (0.53) | PTGS1PTGS2 | |
| SCHEMBL4587680 | 0.83 | PTGS2 (0.59) | PTGS1PTGS2L3MBTL1LMNA | |
| SCHEMBL19053583 | 0.81 | GRM1 (0.44) | PTGS1PTGS2TDP1KDM4EHPGD | |
| SCHEMBL21105019 | 0.75 | PTGS2 (0.48) | PTGS1PTGS2KDM4EHPGDKMT2A | |
| SCHEMBL20034001 | 0.75 | GCGR (0.44) | PTGS1PTGS2AKT2BRD4CHEK1 | |
| SCHEMBL11948735 | 0.73 | ADORA1 (0.47) | CHEK1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL11789345 | 0.73 | PDE10A (0.49) | KDM4ESMN1; SMN2GRM1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11659766-B2 | Organic semiconductor material for electron transport | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-11659766-B2 | Organic semiconductor material for electron transport | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-11345688-B2 | Compound, preparing method therefor, and organic light emitting element comprising same | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-05-31 | — | — | US | disclosed |
| US-20190189933-A1 | ORGANIC SEMICONDUCTOR MATERIAL FOR ELECTRON TRANSPORT | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2019-06-20 | — | — | US | disclosed |
| EP-1556364-A4 | ISOTHIAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | CJ CORP (KR) | 2008-04-16 | — | — | EP | disclosed |
| US-6967213-B2 | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CJ CORP. (KR) | 2005-11-22 | — | — | US | disclosed |
| EP-1556364-A1 | ISOTHIAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | CJ Corp. (KR) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004035553-A1 | ISOTHIAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME | CJ CORP. (KR) | 2004-04-29 | — | — | WO | disclosed |
| US-20040072884-A1 | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CJ CORP. (KR) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072884-A1 | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CYP3A5, CYP2C9, CYP2C19 | PTGS1 31/4885PTGS2 152/4885TDP1 2261/4885 |
| US-11345688-B2 | Compound, preparing method therefor, and organic light emitting element comprising same | CYP4F11, CYP4A11, WEE2 | PTGS1 821/4885PTGS2 1441/4885TDP1 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.