Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10336149 | 0.83 | HSD11B1 (0.50) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL6317037 | 0.81 | HSD11B1 (0.48) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL7534584 | 0.81 | HSD11B1 (0.48) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL25908970 | 0.81 | HSD11B1 (0.48) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL14855368 | 0.79 | HSD11B1 (0.47) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL2134534 | 0.79 | AKT1 (0.48) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL18131923 | 0.78 | RECQL (0.48) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL14247670 | 0.76 | RECQL (0.52) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL5552448 | 0.76 | KDM4E (0.46) | HSD11B1RAB9AHPGDNPC1KMT2A | |
| SCHEMBL5552452 | 0.76 | KDM4E (0.46) | HSD11B1RAB9AHPGDNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537230-A4 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | APPLERA CORP (US) | 2008-06-18 | — | — | EP | disclosed |
| EP-1537230-A1 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | Applera Corporation (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040146959-A1 | Fluorescent enzyme assay methods and compositions | APPLIED BIOSYSTEMS, LLC | 2004-07-29 | — | — | US | disclosed |
| WO-2004022773-A1 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | APPLERA CORPORATION (US) | 2004-03-18 | — | — | WO | disclosed |