SCHEMBL6317037

SCHEMBL6317037

CN(C=O)C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.48
RAB9A P51151 2/20 0.48
CES2 O00748 5/20 0.48
CES1 P23141 5/20 0.48
RECQL P46063 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HPGD P15428 2/20 0.44
EGFR P00533 2/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 1/20 0.43
DAO P14920 1/20 0.42
TSHR P16473 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10336149 0.84 HSD11B1 (0.50) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL7534584 0.83 HSD11B1 (0.48) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL25908970 0.83 HSD11B1 (0.48) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL14855368 0.81 HSD11B1 (0.47) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL4585829 0.81 HSD11B1 (0.47) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL2134534 0.81 AKT1 (0.48) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL14855163 0.79 KDM4E (0.53) RAB9AALDH1A1NPC1KMT2AKDM4E
SCHEMBL18131923 0.79 RECQL (0.48) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL5552448 0.78 KDM4E (0.46) HSD11B1RAB9ACES2CES1RECQL
SCHEMBL14247669 0.78 RECQL (0.52) HSD11B1RAB9ARECQLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024085607-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-04-25 WO disclosed
WO-2024080748-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-04-18 WO disclosed
WO-2024063592-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-03-28 WO disclosed
WO-2024054010-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-03-14 WO disclosed
WO-2024053991-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-03-14 WO disclosed
WO-2024049067-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-03-07 WO disclosed
WO-2024043698-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-02-29 WO disclosed
WO-2024043703-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME 주식회사 엘지화학 2024-02-29 WO disclosed
WO-2024010336-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2024-01-11 WO disclosed
WO-2023239193-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
WO-2012173572-A1 STEREOSELECTIVE SYNTHESIS OF HIGHLY SUBSTITUTED ENAMIDES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2012-12-20 WO disclosed
WO-2012173572-A1 STEREOSELECTIVE SYNTHESIS OF HIGHLY SUBSTITUTED ENAMIDES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2012-12-20 WO disclosed
US-6951876-B2 Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents PFIZER, INC. (US) 2005-10-04 US disclosed
US-6649636-B1 Cyclooxygenase inhibitors PFIZER INC. 2003-11-18 US disclosed
EP-1104759-B1 Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents PFIZER PROD INC (US) 2003-10-22 EP disclosed
US-6603008-B1 Inhibit the biosynthesis of prostaglandins by intervention of the action of the enzyme cyclooxygenase on arachidonic acid PFIZER INC. 2003-08-05 US disclosed
US-20030144280-A1 Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents PFIZER INC. (US) 2003-07-31 US disclosed
EP-1104760-B1 Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents PFIZER PROD INC (US) 2003-03-12 EP disclosed
EP-1104759-A1 Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents Pfizer Products Inc. (US) 2001-06-06 EP disclosed
EP-1104760-A1 Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents Pfizer Products Inc. (US) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144280-A1 Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents PTGS1, PTGS2, SULT2A1 HSD11B1 56/4885RAB9A 3772/4885CES2 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.