Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 9/20 | 1.00 |
| ▸ | PTPN13 | Q12923 | 3/20 | 1.00 |
| ▸ | CTSL | P07711 | 2/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | CTSS | P25774 | 2/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361459 | 1.00 | PTPRC (1.00) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL30087501 | 1.00 | PTPRC (1.00) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL22321739 | 0.97 | PTPRC (0.94) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL29538970 | 0.97 | PTPRC (0.94) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL8610211 | 0.95 | PTPRC (0.91) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL25797323 | 0.87 | PTPRC (0.76) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL22336186 | 0.86 | PTPRC (0.76) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL22336242 | 0.86 | PTPRC (0.76) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL22008429 | 0.86 | PTPRC (0.75) | PTPRCPTPN13CTSLPTPN1CTSS | |
| SCHEMBL20572260 | 0.86 | PTPRC (0.75) | PTPRCPTPN13CTSLPTPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3384007-B1 | IMPROVED METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | BEIHAO STEM CELL AND REGENERATIVE MEDICINE RES INSTITUTE CO LTD (CN) | 2024-03-27 | — | — | EP | claimed |
| EP-3019596-B1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN LTD (CN) | 2023-07-05 | — | — | EP | claimed |
| WO-2023285654-A2 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | DOMPE' FARMACEUTICI SPA (IT) | 2023-01-19 | — | — | WO | claimed |
| EP-4119145-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2023-01-18 | — | — | EP | claimed |
| WO-2022181515-A1 | COMBINATION THERAPY WITH PD-1 SIGNAL INHIBITOR | 国立大学法人京都大学 | 2022-09-01 | — | — | WO | claimed |
| WO-2017004167-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2017-01-05 | — | — | WO | claimed |
| US-9492408-B2 | Protection from chemical-induced acute lung injury | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2016-11-15 | — | — | US | claimed |
| US-20160145581-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN, LTD. (CN) | 2016-05-26 | — | — | US | claimed |
| US-20150119468-A1 | PROTECTION FROM CHEMICAL-INDUCED ACUTE LUNG INJURY | University of Pittsburgh–of the Commonwealth System of Higher Education (US) | 2015-04-30 | — | — | US | claimed |
| US-8778620-B2 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2014-07-15 | — | — | US | claimed |
| US-20130130279-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2013-05-23 | — | — | US | claimed |
| US-20120309029-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2012-12-06 | — | — | US | claimed |
| US-8227202-B2 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2012-07-24 | — | — | US | claimed |
| EP-2304436-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT | Nodality, Inc. (US) | 2011-04-06 | — | — | EP | claimed |
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | claimed |
| EP-2179037-A2 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | Nodality, Inc. (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2010006291-A1 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT | NODALITY, INC. (US) | 2010-01-14 | — | — | WO | claimed |
| US-20100009364-A1 | Methods for diagnosis, prognosis and methods of treatment | NODALITY, INC. (US) | 2010-01-14 | — | — | US | claimed |
| US-20090098594-A1 | Methods for diagnosis prognosis and methods of treatment | NODALITY, INC. (US) | 2009-04-16 | — | — | US | claimed |
| WO-2009025847-A2 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT | NODALITY, INC. (US) | 2009-02-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CSF3R, CSF1R, ATM | PTPRC 42/4885PTPN13 37/4885CTSL 1076/4885 |
| US-20160145581-A1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | AHCY, GSKIP, AHCYL1 | PTPRC 2167/4885PTPN13 1716/4885CTSL 3735/4885 |
| US-20150119468-A1 | PROTECTION FROM CHEMICAL-INDUCED ACUTE LUNG INJURY | DUSP10, CASP10, PHF20 | PTPRC 139/4885PTPN13 66/4885CTSL 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.