Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586464 | 1.00 | PABPC1 (0.52) | PABPC1ALDH1A1GFERCARM1PRMT6 | |
| SCHEMBL4585512 | 0.89 | MAPT (0.57) | PABPC1ALDH1A1CARM1PRMT6MAPT | |
| SCHEMBL4586746 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CARM1PRMT6SMN1; SMN2KMT2A | |
| SCHEMBL4586269 | 0.84 | CARM1 (0.47) | PABPC1CARM1PRMT6SMN1; SMN2KMT2A | |
| SCHEMBL4586330 | 0.81 | CARM1 (0.44) | CARM1PRMT6KCNH2 | |
| SCHEMBL31152659 | 0.77 | POLB (0.65) | PABPC1ALDH1A1GFERCCR6GAA | |
| SCHEMBL4240045 | 0.77 | ALDH1A1 (0.47) | PABPC1ALDH1A1GFERCCR6GAA | |
| SCHEMBL4236028 | 0.77 | ALDH1A1 (0.47) | PABPC1ALDH1A1GFERCCR6GAA | |
| SCHEMBL5871773 | 0.75 | KCNH2 (0.62) | ALDH1A1KCNH2GAAHSD17B10MAPT | |
| SCHEMBL7289534 | 0.74 | KMT2A (0.70) | ALDH1A1SMN1; SMN2SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1896023-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006138259-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-12-28 | — | — | WO | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |