Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586464 | 0.85 | PABPC1 (0.52) | ALDH1A1SMN1; SMN2CARM1PRMT6KMT2A | |
| SCHEMBL4586375 | 0.85 | PABPC1 (0.52) | ALDH1A1SMN1; SMN2CARM1PRMT6KMT2A | |
| SCHEMBL4586330 | 0.84 | CARM1 (0.44) | EPHX2CARM1PRMT6BCHEACHE | |
| SCHEMBL4585512 | 0.84 | MAPT (0.57) | ALDH1A1LMNACARM1PRMT6 | |
| SCHEMBL4586269 | 0.80 | CARM1 (0.47) | LMNASMN1; SMN2CARM1PRMT6CCR5 | |
| SCHEMBL4242742 | 0.79 | UBE2M (0.46) | EPHX2BCHEACHEBACE1EPHX1 | |
| SCHEMBL2172826 | 0.75 | EPHX2 (0.51) | EPHX2EPHX1 | |
| SCHEMBL5535037 | 0.75 | BCHE (0.72) | ALDH1A1EPHX2CHRM4BCHEACHE | |
| SCHEMBL4242736 | 0.74 | EPHX2 (0.49) | EPHX2MEN1KMT2AATMEPHX1 | |
| SCHEMBL4249067 | 0.74 | EPHX2 (0.46) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |