Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 18/20 | 0.54 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14584579 | 0.85 | KIF11 (0.51) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4966633 | 0.81 | MAP1LC3B (0.57) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4586189 | 0.80 | MAP1LC3B (0.58) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4965348 | 0.79 | KIF11 (0.56) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4586389 | 0.79 | KIF11 (0.45) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4965048 | 0.78 | MAP1LC3B (0.53) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4965044 | 0.78 | MAP1LC3B (0.53) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4376437 | 0.77 | KIF11 (0.78) | MAP1LC3BKIF11KIF23KCNH2CYP3A4 | |
| SCHEMBL4498513 | 0.76 | KIF11 (0.66) | MAP1LC3BHTTKIF11KIF23KCNH2 | |
| SCHEMBL4628175 | 0.76 | KIF11 (0.59) | MAP1LC3BHTTKIF11KIF23KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622878-A4 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2008-04-09 | — | — | EP | claimed |
| US-20070032536-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-02-08 | — | — | US | claimed |
| EP-1622878-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2006-02-08 | — | — | EP | claimed |
| WO-2004103282-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-12-02 | — | — | WO | claimed |
| EP-1622878-A4 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20070032536-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032536-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032536-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-02-08 | — | — | US | disclosed |
| EP-1622878-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004103282-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032536-A1 | Compounds, compositions and methods | ALPP, PCNA, MKI67 | MAP1LC3B 1936/4885HTT 3141/4885KIF11 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.