Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587399 | 0.90 | ALDH1A1 (0.38) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| Trifluoroacetic Acid SCHEMBL5050802 | 0.87 | CISD1 (0.35) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| Trifluoroacetic Acid SCHEMBL2995753 | 0.87 | CISD1 (0.35) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| SCHEMBL2996479 | 0.86 | DYRK3 (0.42) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| SCHEMBL2996481 | 0.86 | DYRK3 (0.42) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| SCHEMBL2994948 | 0.84 | KMT2A (0.41) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| SCHEMBL2994951 | 0.84 | KMT2A (0.41) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| SCHEMBL4587397 | 0.84 | ALDH1A1 (0.38) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| SCHEMBL4587403 | 0.84 | ALDH1A1 (0.38) | IGF1RMEN1KMT2AALDH1A1CISD1 | |
| Trifluoroacetic Acid SCHEMBL4089200 | 0.83 | DYRK3 (0.39) | IGF1RMEN1KMT2AALDH1A1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879563-A4 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1879563-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006132739-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-14 | — | — | WO | disclosed |