SCHEMBL4586536

SCHEMBL4586536

CC(C)COC(=O)CN(C)C(=N)N

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.37
CA2 P00918 10/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
TSHR P16473 4/20 0.36
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
ITGB3 P05106 1/20 0.31
ITGA2B P08514 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25515864 0.88 CA1 (0.34) CA1CA2CA12CA9NOS3
SCHEMBL12261562 0.86 CA1 (0.37) CA1CA2CA12CA9NOS3
SCHEMBL25515999 0.86 NOS3 (0.40) CA1CA2CA12CA9NOS3
SCHEMBL25515949 0.83 NOS3 (0.31) CA1CA2CA12CA9NOS3
SCHEMBL24450207 0.83 CHRNB2 (0.42) CA1CA2CA12CA9NOS3
SCHEMBL13850903 0.83 ALDH1A1 (0.39) CA1CA2CA12CA9NOS3
SCHEMBL19152428 0.83 CA1 (0.42) CA1CA2CA12CA9NOS3
SCHEMBL18119724 0.81 NOS3 (0.41) CA1CA2CA12CA9NOS3
Hydrochloric Acid SCHEMBL31410772 0.81 CHRNB2 (0.41) CA1CA2CA12CA9NOS3
SCHEMBL4137961 0.81 KDM4E (0.44) CA1CA2CA12CA9NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080254198-A1 Method of Preparing Creatine Ester Salts and Uses Thereof BIO-ENGINEERED SUPPLEMENTS & NUTRITION, INC. (US) 2008-10-16 US claimed