SCHEMBL4586703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2314927	0.91	MPO (0.59)	MPOKDM4EALOX15HSD17B10CYP2C9
	SCHEMBL2315714	0.89	MPO (0.62)	MPOKDM4EALOX15BACE1HTT
	SCHEMBL24672650	0.85	MPO (0.53)	MPOKDM4EALOX15HSD17B10CYP2C9
	SCHEMBL3967782	0.83	MPO (1.00)	MPOKDM4EALOX15BACE1FAAH
	SCHEMBL9336197	0.82	MPO (0.49)	MPOKDM4EALOX15HSD17B10CYP2C9
	SCHEMBL30275949	0.81	KDM4E (0.56)	MPOKDM4EALOX15HSD17B10CYP2C9
	Hydrochloric Acid SCHEMBL9252817	0.81	MPO (0.47)	MPOKDM4EALOX15HSD17B10CYP2C9
	SCHEMBL14598909	0.79	CYP2D6 (0.58)	MPOALOX15CYP2C9ALDH1A1LMNA
	SCHEMBL18754072	0.78	L3MBTL1 (0.54)	KDM4EHTTPKMALDH1A1LMNA
	SCHEMBL9388542	0.78	MPO (0.88)	MPOKDM4EALOX15BACE1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.