Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10494888 | 0.98 | GAA (0.51) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| SCHEMBL11151986 | 0.91 | GAA (0.53) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| Hydrochloric Acid SCHEMBL11155467 | 0.88 | GAA (0.54) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| SCHEMBL462467 | 0.86 | KDM4E (0.49) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| SCHEMBL10494910 | 0.86 | ALOX15 (0.47) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| SCHEMBL11150521 | 0.85 | GAA (0.55) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| Hydrochloric Acid SCHEMBL10494922 | 0.85 | ALOX15 (0.50) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| Hydrochloric Acid SCHEMBL11357598 | 0.85 | KDM4E (0.51) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| SCHEMBL5712797 | 0.84 | MAPT (0.53) | ALDH1A1GAAKMT2AUSP2KDM4E | |
| Hydrochloric Acid SCHEMBL11158509 | 0.84 | GAA (0.58) | ALDH1A1GAAKMT2AUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| WO-2015086676-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2015-06-18 | — | — | WO | disclosed |
| EP-1353638-A4 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2008-12-03 | — | — | EP | disclosed |
| US-6908493-B2 | Couplers for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2005-06-21 | — | — | US | disclosed |
| US-20040205909-A1 | Novel couplers for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY | 2004-10-21 | — | — | US | disclosed |
| US-6765093-B2 | 4-(3-AMINO-2-HYDROXYPROPOXY)-M-PHENYLENEDIAMINE COUPLERS; 3-AMINO GROUP IS OPTIONALLY SUBSTITUTED | THE PROCTER & GAMBLE COMPANY | 2004-07-20 | — | — | US | disclosed |
| EP-1359888-A1 | COUPLERS FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-1353638-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | Clairol Incorporated (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020144700-A1 | Couplers for oxidative coloration of hair | CLAIROL INCORPORATED | 2002-10-10 | — | — | US | disclosed |
| US-20020138919-A1 | Novel couplers for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2002-10-03 | — | — | US | disclosed |
| WO-2002058656-A1 | NOVEL COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P&G - CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| WO-2002058659-A1 | COUPLERS FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| US-4888025-A | 1-PHENOXY-3-AMINOPROPAN-2-OL | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020138919-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | ALDH1A1 14/4885GAA 4701/4885KMT2A 1962/4885 |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | KRT18, VIM, SORD | ALDH1A1 1145/4885GAA 4553/4885KMT2A 1695/4885 |
| US-20040205909-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | ALDH1A1 14/4885GAA 4701/4885KMT2A 1962/4885 |
| US-20020144700-A1 | Couplers for oxidative coloration of hair | CBR1, CBR3, MT-CO1 | ALDH1A1 37/4885GAA 4787/4885KMT2A 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.