Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16144355 | 0.85 | MAPT (0.66) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL16212817 | 0.78 | MAPT (0.66) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL6140132 | 0.77 | PGR (0.50) | LMNAARPGRHIF1AKMT2A | |
| SCHEMBL11800162 | 0.76 | PGR (0.67) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL372672 | 0.75 | CYP3A4 (0.74) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL11696763 | 0.75 | CYP3A4 (0.74) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL31432443 | 0.75 | CYP3A4 (0.74) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL354296 | 0.75 | CYP3A4 (0.74) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL8853780 | 0.75 | CYP3A4 (0.74) | MAPTLMNAARPGRHIF1A | |
| SCHEMBL11694460 | 0.75 | CYP3A4 (0.74) | MAPTLMNAARPGRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361645-B2 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AG (DE) | 2008-04-22 | — | — | US | claimed |