Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816069 | 0.82 | ENPP2 (0.35) | ANO1SLC6A2SLC6A4IDO1 | |
| SCHEMBL2279322 | 0.81 | HTR2A (0.38) | CXCR2CXCR1IDO1 | |
| SCHEMBL457099 | 0.78 | DPP4 (0.32) | ANO1SLC6A4IDO1AGXT | |
| SCHEMBL16041037 | 0.78 | IDO1 (0.53) | SLC6A2SLC6A4SLC6A3IDO1AGXT | |
| SCHEMBL18037330 | 0.77 | ENPP2 (0.38) | CXCR2CXCR1IDO1AGXT | |
| SCHEMBL10213877 | 0.75 | LMNA (0.35) | CXCR2CXCR1F2RL1 | |
| SCHEMBL13197054 | 0.74 | GABRA1 (0.38) | CXCR2CXCR1F2RL1 | |
| SCHEMBL19150350 | 0.73 | CXCR1 (0.38) | CXCR2CXCR1F2RL1SLC6A2SLC6A4 | |
| SCHEMBL31071985 | 0.73 | CXCR2 (0.34) | CXCR2CXCR1IDO1AGXT | |
| SCHEMBL21767560 | 0.73 | CXCR2 (0.34) | CXCR2CXCR1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |