SCHEMBL4587314

SCHEMBL4587314

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)[O-].CC(C)C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)[O-].[Mn+2]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC15A2 Q16348 1/20 0.39
OPRK1 P41145 3/20 0.39
ERAP2 Q6P179 3/20 0.39
ERAP1 Q9NZ08 2/20 0.39
LNPEP Q9UIQ6 2/20 0.39
NTSR2 O95665 1/20 0.36
NTSR1 P30989 1/20 0.36
GHSR Q92847 3/20 0.36
NPY4R P50391 4/20 0.35
NPY1R P25929 3/20 0.35
NPY2R P49146 3/20 0.35
NPY5R Q15761 2/20 0.35
REN P00797 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2815939 0.98 SLC15A2 (0.39) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL5792595 0.91 SLC15A2 (0.44) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL5598772 0.90 ERAP2 (0.48) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL5598767 0.90 ERAP2 (0.48) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL4588260 0.90 SLC15A2 (0.42) SLC15A2ERAP2ERAP1LNPEPGHSR
SCHEMBL2815934 0.90 ERAP2 (0.47) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL4587311 0.90 ERAP2 (0.47) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL4588807 0.89 SLC15A2 (0.41) SLC15A2OPRK1GHSR
SCHEMBL30906004 0.89 ERAP2 (0.44) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL29937046 0.89 ERAP2 (0.47) SLC15A2OPRK1ERAP2ERAP1LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255032-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN PROCYTE CORPORATION (US) 2008-10-16 US disclosed
US-7384916-B2 Methods and compositions for preventing and treating aging or photodamaged skin PROCYTE CORPORATION (US) 2008-06-10 US disclosed
US-20060246029-A1 Methods and compositions for preventing and treating aging or photodamaged skin PROCYTE CORPORATION (US) 2006-11-02 US disclosed
US-20060018851-A1 Methods and compositions for preventing and treating hyperpigmentation of skin PROCYTE CORPORATION (US) 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246029-A1 Methods and compositions for preventing and treating aging or photodamaged skin RBP1, RBP4, SOD1 SLC15A2 2656/4885OPRK1 4363/4885ERAP2 576/4885
US-20060018851-A1 Methods and compositions for preventing and treating hyperpigmentation of skin RBP1, RBP4, MC1R SLC15A2 1582/4885OPRK1 2506/4885ERAP2 1179/4885
US-20080255032-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN RBP1, RBP4, SOD1 SLC15A2 2656/4885OPRK1 4363/4885ERAP2 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.