SCHEMBL2815939

SCHEMBL2815939

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)[O-].CC(C)C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)[O-].[Cu+2]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC15A2 Q16348 1/20 0.39
OPRK1 P41145 3/20 0.39
ERAP2 Q6P179 3/20 0.39
ERAP1 Q9NZ08 2/20 0.39
LNPEP Q9UIQ6 2/20 0.39
NTSR2 O95665 1/20 0.36
NTSR1 P30989 1/20 0.36
GHSR Q92847 3/20 0.36
NPY4R P50391 4/20 0.35
NPY1R P25929 3/20 0.35
NPY2R P49146 3/20 0.35
NPY5R Q15761 2/20 0.35
REN P00797 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4587314 0.98 SLC15A2 (0.39) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL5792595 0.93 SLC15A2 (0.44) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL5598772 0.90 ERAP2 (0.48) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL5598767 0.90 ERAP2 (0.48) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL2247601 0.90 SLC15A2 (0.42) SLC15A2ERAP2ERAP1LNPEPGHSR
SCHEMBL2815934 0.90 ERAP2 (0.47) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL4587311 0.90 ERAP2 (0.47) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL2813367 0.89 SLC15A2 (0.41) SLC15A2OPRK1GHSR
SCHEMBL29937046 0.89 ERAP2 (0.47) SLC15A2OPRK1ERAP2ERAP1LNPEP
SCHEMBL30906004 0.89 ERAP2 (0.44) SLC15A2OPRK1ERAP2ERAP1LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 US claimed
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 SLC15A2 2091/4885OPRK1 3494/4885ERAP2 279/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC SLC15A2 1553/4885OPRK1 4365/4885ERAP2 633/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 SLC15A2 2514/4885OPRK1 3605/4885ERAP2 218/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 SLC15A2 3106/4885OPRK1 4602/4885ERAP2 1717/4885
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, CTRC SLC15A2 981/4885OPRK1 4536/4885ERAP2 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.