SCHEMBL4587357

SCHEMBL4587357

C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)[O-].C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)[O-].[Mn+2]

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 16/20 0.42
▸ NPY1R P25929 10/20 0.42
▸ NPY5R Q15761 9/20 0.42
▸ NPY2R P49146 6/20 0.42
▸ NOD1 Q9Y239 1/20 0.39
▸ DPP8 Q6V1X1 1/20 0.35
▸ DPP7 Q9UHL4 1/20 0.35
▸ DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811185 0.97 NPY4R (0.42) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL4588680 0.92 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL28684378 0.90 DPP7 (0.42) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL2244099 0.89 NPY4R (0.44) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30087525 0.87 NOD1 (0.50) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL30472837 0.87 NOD1 (0.50) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL31454130 0.86 NOD1 (0.52) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL29697052 0.86 NOD1 (0.52) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL5598692 0.86 NOD1 (0.52) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL29787128 0.86 NOD1 (0.52) NPY4RNPY1RNPY5RNPY2RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255032-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN PROCYTE CORPORATION (US) 2008-10-16 — — US disclosed
US-7384916-B2 Methods and compositions for preventing and treating aging or photodamaged skin PROCYTE CORPORATION (US) 2008-06-10 — — US disclosed
US-20060246029-A1 Methods and compositions for preventing and treating aging or photodamaged skin PROCYTE CORPORATION (US) 2006-11-02 — — US disclosed
US-20060018851-A1 Methods and compositions for preventing and treating hyperpigmentation of skin PROCYTE CORPORATION (US) 2006-01-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246029-A1 Methods and compositions for preventing and treating aging or photodamaged skin RBP1, RBP4, SOD1 NPY4R 3564/4885NPY1R 2475/4885NPY5R 2478/4885
US-20060018851-A1 Methods and compositions for preventing and treating hyperpigmentation of skin RBP1, RBP4, MC1R NPY4R 3166/4885NPY1R 1480/4885NPY5R 1383/4885
US-20080255032-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING AGING OR PHOTODAMAGED SKIN RBP1, RBP4, SOD1 NPY4R 3564/4885NPY1R 2475/4885NPY5R 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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