Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203385 | 0.83 | PTGDR2 (0.47) | MAPK1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL17868453 | 0.79 | PTGDR2 (0.43) | PTGDR2NPC1CA1CA2CA7 | |
| SCHEMBL19513345 | 0.79 | GRM5 (0.40) | GRM5S1PR1CA1CA2CA7 | |
| SCHEMBL5930947 | 0.76 | KCNA5 (0.37) | MAPK14 | |
| SCHEMBL12798314 | 0.74 | PTGDR2 (0.43) | MAPK1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL29417721 | 0.72 | PTGDR2 (0.48) | MAPK1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL795719 | 0.72 | PTGDR2 (0.48) | MAPK1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL135165 | 0.71 | PTGDR2 (0.49) | MAPK1HSD17B10PTGDR2MEN1KMT2A | |
| SCHEMBL20465747 | 0.71 | PYCR1 (0.46) | MAPK1HSD17B10PTGDR2AKR1B1MEN1 | |
| SCHEMBL507839 | 0.71 | PYCR1 (0.46) | MAPK1HSD17B10PTGDR2AKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706394-B1 | PREPARATION OF ESCITALOPRAM | REDDYS LAB INC DR (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-1706394-A4 | PREPARATION OF ESCITALOPRAM | REDDYS LAB INC DR (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1706394-A1 | PREPARATION OF ESCITALOPRAM | Dr. Reddy's Laboratories, Inc. (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005047274-A1 | PREPARATION OF ESCITALOPRAM | DR. REDDY'S LABORATORIES, INC. (US) | 2005-05-26 | — | — | WO | disclosed |