Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12798314 | 0.89 | PTGDR2 (0.43) | PTGDR2SLC6A2SLC6A4S100A4BCL2 | |
| SCHEMBL1988581 | 0.85 | PTGDR2 (0.46) | PTGDR2SLC6A2SLC6A4NPC1ALDH1A1 | |
| SCHEMBL31468792 | 0.83 | PTGDR2 (0.37) | PTGDR2SLC6A2SLC6A4CA1CA2 | |
| SCHEMBL12849035 | 0.83 | KDM4E (0.45) | PTGDR2ALOX15ALDH1A1MAPTHSD17B10 | |
| SCHEMBL4587479 | 0.83 | MAPK1 (0.41) | PTGDR2SLC6A2SLC6A4CA1CA2 | |
| SCHEMBL29417721 | 0.82 | PTGDR2 (0.48) | PTGDR2ALOX15SLC6A2SLC6A4NPC1 | |
| SCHEMBL795719 | 0.82 | PTGDR2 (0.48) | PTGDR2ALOX15SLC6A2SLC6A4NPC1 | |
| SCHEMBL17868453 | 0.80 | PTGDR2 (0.43) | PTGDR2ALOX15SLC6A2SLC6A4S100A4 | |
| SCHEMBL1047305 | 0.80 | PTGDR2 (0.47) | PTGDR2ALOX15SLC6A2SLC6A4S100A4 | |
| SCHEMBL29870381 | 0.78 | ALOX15 (0.52) | PTGDR2ALOX15SLC6A2SLC6A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626716-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| US-9981955-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-9511056-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-20090202483-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-08-13 | — | — | US | disclosed |
| US-7462683-B2 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070034832-A1 | (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2007-02-15 | — | — | US | disclosed |
| US-20070034832-A1 | (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2007-02-15 | — | — | US | disclosed |
| EP-1717258-A1 | DIHALIDE, POLYMER COMPOUND AND METHOD FOR PRODUCING SAME | Tokyo Institute of Technology (JP) | 2006-11-02 | — | — | EP | disclosed |
| EP-1325054-B1 | TWISTED POLYMERS, USES THEREOF AND PROCESSES FOR THE PREPARATION OF STATISTICAL COPOLYMERS | CAMBRIDGE DISPLAY TECH LTD (GB) | 2006-07-19 | — | — | EP | disclosed |
| US-6949291-B2 | Twisted polymers, uses thereof and processes for the preparation of statistical copolymers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2005-09-27 | — | — | US | disclosed |
| US-20040097699-A1 | Twisted polymers, uses thereof and processes for the preparation of statistical copolymers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | HSPA4L, HDHD5, MRPL21 | PTGDR2 3232/4885ALOX15 3235/4885SLC6A2 3577/4885 |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | PTGDR2 4829/4885ALOX15 2962/4885SLC6A2 4103/4885 |
| US-20090202483-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | PTGDR2 3993/4885ALOX15 2436/4885SLC6A2 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.