Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943840 | 0.88 | ALDH1A1 (0.47) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL3941985 | 0.85 | ALDH1A1 (0.46) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL3948275 | 0.84 | ALDH1A1 (0.48) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL5151439 | 0.84 | ALDH1A1 (0.49) | SERPINE1HTR6ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4588607 | 0.84 | SERPINE1 (0.44) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL4588618 | 0.84 | SERPINE1 (0.44) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL3951748 | 0.82 | ALDH1A1 (0.45) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL3947208 | 0.82 | ALDH1A1 (0.47) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL3943632 | 0.82 | ALDH1A1 (0.47) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 | |
| SCHEMBL3952555 | 0.82 | ALDH1A1 (0.47) | SERPINE1BRD4HTR6ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001846-A1 | INDOLE DERIVATIVES AS INHIBITORS OF THE SOLUBLE ADENYLATE CYCLASE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| US-7449459-B2 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AG (DE) | 2008-11-11 | — | — | US | claimed |
| US-20070232605-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | claimed |
| WO-2007107383-A1 | INDOLE DERIVATIVES AS INHIBITORS OF THE SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-2001846-A1 | INDOLE DERIVATIVES AS INHIBITORS OF THE SOLUBLE ADENYLATE CYCLASE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |
| US-7449459-B2 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AG (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7449459-B2 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AG (DE) | 2008-11-11 | — | — | US | disclosed |
| US-7449459-B2 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AG (DE) | 2008-11-11 | — | — | US | disclosed |
| US-20070232605-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070232605-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070232605-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
| WO-2007107383-A1 | INDOLE DERIVATIVES AS INHIBITORS OF THE SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107383-A1 | INDOLE DERIVATIVES AS INHIBITORS OF THE SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232605-A1 | Inhibitors of soluble adenylate cyclase | ADCY1, ADCY2, ADCYAP1R1 | SERPINE1 623/4885BRD4 3944/4885HTR6 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.