Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.51 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377534 | 0.86 | PHLPP2 (0.70) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL113323 | 0.86 | PHLPP2 (0.70) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL186095 | 0.86 | PHLPP2 (0.70) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL344209 | 0.86 | PHLPP2 (0.70) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL27752533 | 0.85 | PHLPP2 (0.68) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL19513949 | 0.85 | PHLPP2 (0.68) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL186093 | 0.85 | PHLPP2 (0.68) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL10649599 | 0.80 | ENPP2 (0.52) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL6559437 | 0.79 | CYP1A2 (0.62) | PHLPP2CYP1A2SUMO2SUMO1SENP7 | |
| SCHEMBL7624223 | 0.79 | CYP1A2 (0.62) | PHLPP2CYP1A2SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080112905-A1 | Flavonoid Complexes | MERCK PATENT GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080112905-A1 | Flavonoid Complexes | C9, C1R, CYC1 | PHLPP2 2786/4885CYP1A2 343/4885SUMO2 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.