SCHEMBL4589132

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL277185	0.86	TSHR (0.50)	MAPTCA1CA2CA12CA9
	SCHEMBL276357	0.86	MAPT (0.42)	MAPTCA1CA2CA12CA9
	SCHEMBL28045016	0.83	ALDH1A1 (0.42)	MAPTTDP1TSHRALDH1A1CYP4A11
	SCHEMBL4486192	0.82	TAAR1 (0.52)	MAPTCA1CA2CA12CA9
	SCHEMBL28827835	0.82	MAPT (0.47)	MAPTTDP1ALDH1A1RAB9A
	SCHEMBL14042112	0.82	TAAR1 (0.52)	MAPTCA1CA2CA12CA9
	SCHEMBL4484678	0.82	TAAR1 (0.52)	MAPTCA1CA2CA12CA9
	SCHEMBL31376526	0.82	CA1 (0.52)	MAPTCA1CA2CA12CA9
	SCHEMBL867166	0.82	CA1 (0.52)	MAPTCA1CA2CA12CA9
	SCHEMBL14331342	0.82	MAPT (0.45)	MAPTCA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.