Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRG | P23470 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590019 | 0.88 | TAAR1 (0.40) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL4590140 | 0.82 | TAAR1 (0.41) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL97274 | 0.81 | TAAR1 (0.57) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL4558176 | 0.77 | TAAR1 (0.40) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL4590021 | 0.74 | CHRM2 (0.43) | TAAR1PNMTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4589469 | 0.73 | TAAR1 (0.41) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL4535289 | 0.73 | PTPRC (0.37) | TAAR1PNMTIDO1SMN1; SMN2NPSR1 | |
| SCHEMBL10454588 | 0.70 | PNMT (0.47) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL14609134 | 0.70 | TAAR1 (0.47) | TAAR1PNMTIDO1CYP1A2CYP3A4 | |
| SCHEMBL1338205 | 0.67 | TAAR1 (0.54) | TAAR1PNMTIDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937656-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS BETA 2 ADRENOCEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007027134-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-03-08 | — | — | WO | disclosed |