SCHEMBL97274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1338205	0.83	TAAR1 (0.54)	TAAR1PNMTIDO1SMN1; SMN2
	SCHEMBL30444061	0.83	TAAR1 (0.54)	TAAR1PNMTIDO1SMN1; SMN2
	SCHEMBL14609134	0.83	TAAR1 (0.47)	TAAR1PNMTIDO1CYP1A2GLA
	SCHEMBL4589466	0.81	TAAR1 (0.42)	TAAR1PNMTIDO1CYP1A2GLA
	SCHEMBL26599109	0.81	AKR1B1 (0.38)	TAAR1PNMTIDO1CYP1A2GLA
	SCHEMBL28022828	0.81	ALDH1A1 (0.39)	TAAR1PNMTIDO1ALDH1A1KDM4E
	SCHEMBL10454588	0.79	PNMT (0.47)	TAAR1PNMTIDO1CYP1A2GLA
	SCHEMBL6194272	0.79	PNMT (0.56)	TAAR1PNMTIDO1CYP1A2GLA
	SCHEMBL10690855	0.77	TAAR1 (0.63)	TAAR1PNMTIDO1CYP1A2GLA
	SCHEMBL97848	0.77	TAAR1 (0.52)	TAAR1CYP1A2GLACYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.