Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20907444 | 0.83 | TP53 (0.61) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL64400 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL20897465 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL5322691 | 0.82 | KDM4E (0.67) | ALDH1A1MAPTCXCR3SMN1; SMN2HPGD | |
| SCHEMBL13979594 | 0.80 | CXCR3 (0.49) | KMT2ACXCR3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2951325 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL4589173 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2HPGD | |
| SCHEMBL5742108 | 0.78 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL4116463 | 0.78 | MAPT (0.69) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL64850 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312215-A1 | Substituted [1,4]-diazepanes as CXCR3 antagonists and their use in the treatment of inflammatory disorders | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312215-A1 | Substituted [1,4]-diazepanes as CXCR3 antagonists and their use in the treatment of inflammatory disorders | CXCR3, CXCR1, CX3CR1 | ALDH1A1 1053/4885MAPT 4702/4885KMT2A 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.