Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110493 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL25863260 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL7111536 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL25863256 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL25863258 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL12355412 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL2249046 | 1.00 | AR (1.00) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL25863521 | 0.96 | AR (0.93) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL25863642 | 0.96 | AR (0.93) | ARLMNAMAPTCYP19A1KMT2A | |
| SCHEMBL25863523 | 0.96 | AR (0.93) | ARLMNAMAPTCYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042352-B1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | RES TRIANGLE INST (US) | 2007-07-25 | — | — | EP | claimed |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | RESEARCH TRIANGLE INSTITUTE (US) | 2004-05-20 | — | — | US | claimed |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | COOK C EDGAR (US) | 2002-08-01 | — | — | US | claimed |
| US-6369047-B2 | ESTR-4-EN-3-ONE DERIVATIVES WITH ENHANCED ACTIVITY RELATIVE TO TESTOSTERONE DUE TO ENHANCED POTENCY; REDUCTION IN SIZE OF SKIN PATCHES | RESEARCH TRIANGLE INSTITUTE | 2002-04-09 | — | — | US | claimed |
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | COOK C EDGAR (US) | 2002-01-03 | — | — | US | claimed |
| US-5952319-A | CONTROLLING MALE FERTILITY IN MAMMAL | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-14 | — | — | US | claimed |
| US-7361645-B2 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| EP-1353938-B1 | ANDROGENIC 7-SUBSTITUTED 11-HALOGENATED STEROIDS | BAYER SCHERING PHARMA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20070298456-A1 | Microbiological process for the production of 7-substitued 11-hydroxy steroids, 7,17-substituted 11-halogen steroids, and uses thereof | ZORN LUDWIG | 2007-12-27 | — | — | US | disclosed |
| EP-1042352-B1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | RES TRIANGLE INST (US) | 2007-07-25 | — | — | EP | disclosed |
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-04-07 | — | — | US | disclosed |
| US-6864248-B2 | Androgenic steroid compounds and a method of making and using the same | RESEARCH TRIANGLE INSTITUTE (US) | 2005-03-08 | — | — | US | disclosed |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | RESEARCH TRIANGLE INSTITUTE (US) | 2004-05-20 | — | — | US | disclosed |
| US-6670352-B2 | E.g. 7alpha,11beta-dimethyl-17beta-hydroxyestr-4-en-3-one; controlling male fertility; stereospecific synthesis starting from adrenosterone, and introducing the 7alpha substituent prior to an 11-substituent | RESEARCH TRIANGLE INSTITUTE | 2003-12-30 | — | — | US | disclosed |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | COOK C EDGAR (US) | 2002-08-01 | — | — | US | disclosed |
| US-6369047-B2 | ESTR-4-EN-3-ONE DERIVATIVES WITH ENHANCED ACTIVITY RELATIVE TO TESTOSTERONE DUE TO ENHANCED POTENCY; REDUCTION IN SIZE OF SKIN PATCHES | RESEARCH TRIANGLE INSTITUTE | 2002-04-09 | — | — | US | disclosed |
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | COOK C EDGAR (US) | 2002-01-03 | — | — | US | disclosed |
| US-5952319-A | CONTROLLING MALE FERTILITY IN MAMMAL | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | NR5A1, CYP17A1, SHBG | AR 4/4885LMNA 1964/4885MAPT 4047/4885 |
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | NR5A1, HSD17B11, HSD11B1 | AR 16/4885LMNA 2482/4885MAPT 4298/4885 |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | NR5A1, CYP17A1, SHBG | AR 4/4885LMNA 1964/4885MAPT 4047/4885 |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | NR5A1, CYP17A1, SHBG | AR 4/4885LMNA 1964/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.