SCHEMBL2249046

SCHEMBL2249046

CCCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@H]3[C@H]([C@@H](C)C[C@]12C)[C@H]1CCC(=O)C=C1C[C@H]3C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 6/20 1.00
▸ LMNA P02545 4/20 0.62
▸ MAPT P10636 4/20 0.62
▸ CYP19A1 P11511 6/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ ESR1 P03372 1/20 0.40
▸ PGR P06401 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ ADORA3 P0DMS8 1/20 0.40
▸ CHRM1 P11229 1/20 0.40
▸ TBXA2R P21731 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ PDE3A Q14432 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ USP2 O75604 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110493 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL25863260 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL7111536 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL25863256 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL25863258 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL12355412 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL4589523 1.00 AR (1.00) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL25863521 0.96 AR (0.93) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL25863642 0.96 AR (0.93) ARLMNAMAPTCYP19A1KMT2A
SCHEMBL25863523 0.96 AR (0.93) ARLMNAMAPTCYP19A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070133-A Pharmaceutical compositions containing androgen receptor inhibitors/antagonists, methods and uses 苏州开拓药业股份有限公司 2026-05-19 — — CN claimed
WO-2025051237-A1 PHARMACEUTICAL COMPOSITION CONTAINING ANDROGEN RECEPTOR INHIBITOR/ANTAGONIST, METHOD AND USE 苏州开拓药业股份有限公司 2025-03-13 — — WO claimed
CN-114479317-A UPVC (unplasticized polyvinyl chloride) profile as well as preparation method and application thereof 五行科技股份有限公司 2022-05-13 — — CN claimed
US-10351587-B2 Method of making and using 7α, 11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2019-07-16 — — US claimed
US-20110195942-A1 METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN 2011-08-11 — — US claimed
US-20090023695-A1 METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH 2009-01-22 — — US claimed
EP-1272196-B1 METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA,11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE US GOV HEALTH & HUMAN SERV (US) 2006-08-02 — — EP claimed
US-20050130944-A1 Method of making and using 7alpha,11beta-dimethyl-17beta-hydroxyestr-4-en-3-one 17-undecanoate GOVERNMENT OF THE USA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2005-06-16 — — US claimed
US-20030069215-A1 Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate THE GOVERNMENT OF THE UNITED STATES OF AMERICA, 2003-04-10 — — US claimed
CN-122070133-A Pharmaceutical compositions containing androgen receptor inhibitors/antagonists, methods and uses 苏州开拓药业股份有限公司 2026-05-19 — — CN disclosed
US-12570887-B2 Ultra-high molecular weight (UHMW) branched block copolymer viscosifier for water based drilling fluids SAUDI ARABIAN OIL COMPANY (SA) 2026-03-10 — — US disclosed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 — — US disclosed
US-12391864-B2 Development of ultra-high molecular weight (UHMW) branched block copolymer shale inhibitor for water based drilling fluid SAUDI ARABIAN OIL COMPANY (SA) 2025-08-19 — — US disclosed
US-12378465-B2 Development of ultra-high molecular weight (UHMW) branched block copolymer drag reducer with improved mechanical and chemical stability SAUDI ARABIAN OIL COMPANY (SA) 2025-08-05 — — US disclosed
US-20030130243-A1 Methods of making, using and pharmaceutical formulations comprising 7alpha, 11beta-dimethyl-17beta-hydroxyestra-4, 14-dien-3-one and 17 esters thereof and 17 esters of 7alpha-methyl-17beta-hydroxyestra-4,14-dien-3-one THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, 2003-07-10 — — US disclosed
US-20030069215-A1 Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate THE GOVERNMENT OF THE UNITED STATES OF AMERICA, 2003-04-10 — — US disclosed
US-20030069215-A1 Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate THE GOVERNMENT OF THE UNITED STATES OF AMERICA, 2003-04-10 — — US disclosed
US-20030069215-A1 Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate THE GOVERNMENT OF THE UNITED STATES OF AMERICA, 2003-04-10 — — US disclosed
WO-2001074839-A3 METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA, 11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE US GOV HEALTH & HUMAN SERV (US) 2002-06-13 — — WO disclosed
WO-2001074839-A2 METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA, 11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-10-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023695-A1 METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE HSD17B11, HSD17B13, HSD3B1 AR 518/4885LMNA 1122/4885MAPT 4310/4885
US-20030130243-A1 Methods of making, using and pharmaceutical formulations comprising 7alpha, 11beta-dimethyl-17beta-hydroxyestra-4, 14-dien-3-one and 17 esters thereof and 17 esters of 7alpha-methyl-17beta-hydroxyestra-4,14-dien-3-one HSD17B11, CYP19A1, HSD17B7 AR 244/4885LMNA 927/4885MAPT 4718/4885
US-20110195942-A1 METHOD OF MAKING AND USING 7ALPHA, 11BETA-DIMETHYL-17BETA-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE HSD17B11, HSD17B13, HSD3B1 AR 518/4885LMNA 1122/4885MAPT 4310/4885
US-20050130944-A1 Method of making and using 7alpha,11beta-dimethyl-17beta-hydroxyestr-4-en-3-one 17-undecanoate HSD17B11, HSD17B13, HSD3B1 AR 196/4885LMNA 561/4885MAPT 3648/4885
US-10351587-B2 Method of making and using 7α, 11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate HSD17B11, HSD17B13, CYP19A1 AR 274/4885LMNA 933/4885MAPT 3820/4885
US-12570887-B2 Ultra-high molecular weight (UHMW) branched block copolymer viscosifier for water based drilling fluids FGB, VCL, FUS AR 2282/4885LMNA 1404/4885MAPT 2007/4885
US-20030069215-A1 Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate HSD17B11, CYP19A1, SHBG AR 197/4885LMNA 1173/4885MAPT 3964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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