SCHEMBL4589782

SCHEMBL4589782

C=Cc1cccc2c(CO)cccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 2/20 0.38
ALDH1A1 P00352 2/20 0.35
LMNA P02545 4/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
APOBEC3G Q9HC16 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SLC9A1 P19634 1/20 0.33
ESR2 Q92731 1/20 0.32
NPC1 O15118 2/20 0.32
HTT P42858 2/20 0.32
RAB9A P51151 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1976914 0.88 GCGR (0.39) GCGRALDH1A1LMNAKDM4EMAPT
SCHEMBL29284833 0.83 ALDH1A1 (0.43) ALDH1A1LMNAMAPTTSHRAPOBEC3G
SCHEMBL29434190 0.82 ALDH1A1 (0.48) ALDH1A1LMNATP53TSHRSIRT2
SCHEMBL1554672 0.82 ALDH1A1 (0.48) ALDH1A1LMNATP53TSHRSIRT2
SCHEMBL4503938 0.82 GABRA1 (0.40) ALDH1A1LMNAGABRA1GABRB2SLC9A1
SCHEMBL29568735 0.80 ALDH1A1 (0.44) ALDH1A1LMNATSHRAPOBEC3GGABRA1
SCHEMBL93849 0.80 ALDH1A1 (0.44) ALDH1A1LMNATSHRAPOBEC3GGABRA1
SCHEMBL216868 0.79 ALDH1A1 (0.35) ALDH1A1LMNAMAPTALOX12APOBEC3G
SCHEMBL2647250 0.79 MEN1 (0.42) GCGRALDH1A1LMNAKDM4EMAPT
SCHEMBL2662663 0.79 GCGR (0.38) GCGRLMNAKDM4EMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1386904-B1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORP (JP) 2008-09-17 EP disclosed
US-7037994-B2 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORPORATION (JP) 2006-05-02 US disclosed
US-20040034155-A1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR CORPORATION (JP) 2004-02-19 US disclosed
EP-1386904-A1 Acenaphthylene derivative, polymer, and antireflection film-forming composition JSR Corporation (JP) 2004-02-04 EP disclosed