SCHEMBL216868

SCHEMBL216868

C=Cc1cccc(CO)c1CO

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
APOBEC3G Q9HC16 1/20 0.34
GABRA1 P14867 2/20 0.34
GABRB2 P47870 1/20 0.34
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
LMNA P02545 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
ALOX12 P18054 1/20 0.31
MEN1 O00255 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10618417 0.86 GABRA1 (0.38) ALDH1A1APOBEC3GGABRA1GABRB2GABRG2
SCHEMBL4275363 0.81 ALDH1A1 (0.38) ALDH1A1
SCHEMBL29568735 0.80 ALDH1A1 (0.44) ALDH1A1APOBEC3GGABRA1GABRB2PDCD1
SCHEMBL93849 0.80 ALDH1A1 (0.44) ALDH1A1APOBEC3GGABRA1GABRB2PDCD1
SCHEMBL2651603 0.79 APOBEC3G (0.34) APOBEC3GGABRA1GABRG2GABRB3PDCD1
SCHEMBL487089 0.79 PDXK (0.37) ALDH1A1APOBEC3GGABRA1GABRB2PDCD1
SCHEMBL8955156 0.79 MEN1 (0.42) ALDH1A1APOBEC3GGABRA1GABRG2GABRB3
SCHEMBL4589782 0.79 GCGR (0.38) ALDH1A1APOBEC3GGABRA1GABRB2PDCD1
SCHEMBL29284833 0.78 ALDH1A1 (0.43) ALDH1A1APOBEC3GGABRA1GABRB2PDCD1
SCHEMBL16950434 0.78 PDCD1 (0.48) ALDH1A1APOBEC3GGABRA1GABRB2PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633494-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-04-25 US claimed
US-11633495-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-04-25 US claimed
EP-4056594-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY Birdie Biopharmaceuticals Inc. (KY) 2022-09-14 EP claimed
US-20200353093-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2020-11-12 US claimed
US-20200345860-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2020-11-05 US claimed
US-10780180-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2020-09-22 US claimed
US-10744206-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2020-08-18 US claimed
US-20190269790-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2019-09-05 US claimed
US-20190269789-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2019-09-05 US claimed
US-10328158-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2019-06-25 US claimed
US-20260144888-A1 USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE PIERRE FABRE MEDICAMENT (FR) 2026-05-28 US disclosed
US-20260146088-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2026-05-28 US disclosed
US-20260137822-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY ABDERA THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-4727586-A1 ANTI-CD5 ANTIBODIES AND THEIR USES Synthis Therapeutics, Inc. (US) 2026-04-22 EP disclosed
EP-3494996-B1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS AGENSYS INC (US) 2026-04-15 EP disclosed
WO-2004006753-A2 SGA-72M, A CANCER ASSOCIATED ANTIGEN, AND USES THEREOF SEATTLE GENETICS, INC. (US) 2004-01-22 WO disclosed
WO-2003043583-A2 TREATMENT OF IMMUNOLOGICAL DISORDERS USING ANTI-CD30 ANTIBODIES SEATTLE GENETICS, INC. (US) 2003-05-30 WO disclosed
EP-0961619-A4 HYDROLYZABLE PRODRUGS FOR DELIVERY OF ANTICANCER DRUGS TO METASTATIC CELLS BRISTOL MYERS SQUIBB CO (US) 2001-09-26 EP disclosed
EP-0961619-A1 HYDROLYZABLE PRODRUGS FOR DELIVERY OF ANTICANCER DRUGS TO METASTATIC CELLS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-12-08 EP disclosed
WO-1998013059-A1 HYDROLYZABLE PRODRUGS FOR DELIVERY OF ANTICANCER DRUGS TO METASTATIC CELLS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269790-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-10744206-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-11633494-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-20260146088-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE H1-10, IGSF11, CD99 ALDH1A1 2977/4885APOBEC3G 1182/4885GABRA1 1903/4885
US-20200345860-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-11633495-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-20190269789-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-20260144888-A1 USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE IGF1R, CD44, MUC1 ALDH1A1 3043/4885APOBEC3G 4726/4885GABRA1 242/4885
US-10328158-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-20260137822-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY FCGR2A, FCGR3B, FCGR1A ALDH1A1 3825/4885APOBEC3G 86/4885GABRA1 1923/4885
US-10780180-B2 Compounds and compositions for immunotherapy CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885
US-20200353093-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 ALDH1A1 1617/4885APOBEC3G 1085/4885GABRA1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.