SCHEMBL1740828

SCHEMBL1740828

N=C(N)N(C(=N)Nc1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TAS2R38 P59533 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TP53 P04637 2/20 0.44
TSHR P16473 2/20 0.44
TYR P14679 1/20 0.44
GAA P10253 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 1/20 0.39
GFER P55789 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31696764 0.98 ALDH1A1 (0.42) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL3066412 0.82 MEN1 (0.50) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL458998 0.80 ALDH1A1 (0.46) ALDH1A1KMT2AMAPTGRIN2DGRIN3B
SCHEMBL5961424 0.77 ALDH1A1 (0.42) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL1792956 0.76 ALDH1A1 (0.43) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL109209 0.76 ALDH1A1 (0.43) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL28133735 0.76 HSD17B10 (0.39) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL14868313 0.76 TAS2R38 (0.45) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL5440028 0.75 MMP1 (0.54) NPC1
SCHEMBL5440025 0.75 MMP1 (0.54) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product NITTO KASEI CO., LTD. (JP) 2025-11-25 US disclosed
EP-4174053-B1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO LTD (JP) 2025-11-19 EP disclosed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
CN-115516041-B Curing catalyst for curing polymer, method for producing same, moisture-curable composition, and method for producing cured product 日东化成株式会社 2024-06-28 CN disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO., LTD. (JP) 2023-07-27 US disclosed
EP-4180482-A1 MOISTURE-CURABLE COMPOSITION Nitto Kasei Co., Ltd. (JP) 2023-05-17 EP disclosed
EP-4174053-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT Nitto Kasei Co., Ltd. (JP) 2023-05-03 EP disclosed
US-9376525-B2 Curable composition, and cured synthetic resin using same MIE UNIVERSITY (JP) 2016-06-28 US disclosed
WO-2016012305-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2016-01-28 WO disclosed
US-20150099849-A1 CURABLE COMPOSITION, AND CURED SYNTHETIC RESIN USING SAME MIE UNIVERSITY (JP) 2015-04-09 US disclosed
EP-2837660-A1 CURABLE COMPOSITION, AND CURED SYNTHETIC RESIN USING SAME Mie University (JP) 2015-02-18 EP disclosed
US-8853309-B2 Curable composition and cured product thereof KANEKA CORPORATION (JP) 2014-10-07 US disclosed
EP-2338938-B1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORP (JP) 2013-07-31 EP disclosed
EP-2388297-A1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM Kaneka Corporation (JP) 2011-11-23 EP disclosed
US-20110237723-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORPORATION (JP) 2011-09-29 US disclosed
EP-2338938-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF Kaneka Corporation (JP) 2011-06-29 EP disclosed
EP-2267083-A1 CURABLE COMPOSITION AND CURED MATERIAL Kaneka Corporation (JP) 2010-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product KDM2B, SETDB1, ASH2L ALDH1A1 615/4885TAS2R38 4109/4885HSD17B10 2247/4885
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT KDM2B, SETDB1, ASH2L ALDH1A1 615/4885TAS2R38 4109/4885HSD17B10 2247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.