Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 20/20 | 0.77 |
| ▸ | CTSK | P43235 | 20/20 | 0.77 |
| ▸ | CTSS | P25774 | 18/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109875 | 0.88 | CTSB (0.58) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8104024 | 0.85 | CTSB (1.00) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8096806 | 0.85 | CTSB (1.00) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8123336 | 0.75 | CTSK (0.71) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL4590334 | 0.75 | CTSB (0.44) | CTSBCTSKCTSS | |
| SCHEMBL4590328 | 0.75 | CTSB (0.44) | CTSBCTSKCTSS | |
| SCHEMBL8108888 | 0.75 | CTSB (0.76) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL8104338 | 0.73 | CTSK (1.00) | CTSBCTSKCTSSKCNH2 | |
| SCHEMBL4589989 | 0.72 | ACACB (0.49) | — | |
| SCHEMBL8106040 | 0.72 | CTSB (0.74) | CTSBCTSKCTSSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |