Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 13/20 | 0.44 |
| ▸ | CTSS | P25774 | 13/20 | 0.44 |
| ▸ | CTSK | P43235 | 13/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590334 | 1.00 | CTSB (0.44) | CTSBCTSSCTSKACACB | |
| SCHEMBL4573491 | 0.81 | CTSB (0.63) | CTSBCTSSCTSK | |
| SCHEMBL4590330 | 0.75 | CTSB (0.77) | CTSBCTSSCTSK | |
| SCHEMBL8109875 | 0.73 | CTSB (0.58) | CTSBCTSSCTSKACACB | |
| SCHEMBL4589989 | 0.72 | ACACB (0.49) | ACACB | |
| SCHEMBL4573200 | 0.71 | CTSK (0.57) | CTSBCTSSCTSK | |
| SCHEMBL4589748 | 0.70 | CTSB (0.54) | CTSBCTSSCTSK | |
| SCHEMBL4573253 | 0.69 | CTSK (0.39) | CTSBCTSSCTSKACACB | |
| SCHEMBL4573950 | 0.69 | CTSS (0.45) | CTSBCTSSCTSK | |
| SCHEMBL4573015 | 0.68 | CTSK (0.38) | CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |