Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453524 | 0.71 | GBA1 (0.44) | GBA1HTTKDM4ELMNAGAA | |
| SCHEMBL6922536 | 0.70 | HDAC1 (0.56) | HTTKDM4ELMNASMN1; SMN2HDAC1 | |
| Oxalic Acid SCHEMBL8326149 | 0.69 | AR (0.39) | HDAC1HDAC8HDAC6ARMTOR | |
| SCHEMBL30395614 | 0.69 | GBA1 (0.41) | GBA1SMN1; SMN2MAPTKMT2APTGIR | |
| SCHEMBL25260665 | 0.69 | GBA1 (0.41) | GBA1SMN1; SMN2MAPTKMT2APTGIR | |
| SCHEMBL16231504 | 0.67 | GBA1 (0.53) | GBA1KDM4ESMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL31217239 | 0.67 | EGFR (0.44) | GBA1HTTKDM4ESMN1; SMN2MAPT | |
| SCHEMBL28281535 | 0.67 | NR1H2 (0.62) | HTTKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL8497602 | 0.66 | ALDH1A1 (0.48) | TSHRMTORMEN1KMT2A | |
| SCHEMBL9446233 | 0.65 | NR3C2 (0.51) | HTTHDAC1HDAC8HDAC6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064265-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |