⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919395 | 0.86 | — | — | |
| SCHEMBL789308 | 0.82 | — | — | |
| SCHEMBL789435 | 0.80 | NOS1 (0.35) | — | |
| SCHEMBL2918213 | 0.79 | — | — | |
| SCHEMBL254648 | 0.79 | GBA1 (0.33) | — | |
| SCHEMBL3254586 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL1461367 | 0.77 | CYP2D6 (0.36) | — | |
| SCHEMBL1233220 | 0.76 | — | — | |
| SCHEMBL948954 | 0.76 | — | — | |
| SCHEMBL2917920 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107955-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | ONCONOVA THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | claimed |
| US-20240051975-A1 | NOVEL NAMPT ENZYME AGONIST AND PREPARATION AND USE THEREOF | TSINGHUA UNIVERSITY (CN) | 2024-02-15 | — | — | US | claimed |
| WO-2023230288-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | ONCONOVA THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | claimed |
| CN-117088895-A | Scutellarin compound and preparation method and application thereof | 福建医科大学 | 2023-11-21 | — | — | CN | claimed |
| WO-2023081400-A9 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | claimed |
| WO-2023081400-A1 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-05-11 | — | — | WO | claimed |
| CN-114805438-A | Phosphoacyl-containing TYK2 inhibitor compounds | 正大天晴药业集团股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114716343-A | Novel NAMPT enzyme agonist, preparation and application thereof | 清华大学 | 2022-07-08 | — | — | CN | claimed |
| US-20220128562-A1 | BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF | UNIVERSITY OF KANSAS | 2022-04-28 | — | — | US | claimed |
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | claimed |
| EP-0448774-A2 | Triazinic compounds | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-10-02 | — | — | EP | claimed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | claimed |
| EP-0415371-A2 | Self-extinguishing polymeric compositions | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-03-06 | — | — | EP | claimed |
| EP-0406810-A1 | Self-extinguishing polymeric compositions | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-01-09 | — | — | EP | claimed |
| EP-0201400-B1 | 4-PHENYL PROPYL INDOLE DERIVATIVES AND THEIR SALTS, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1989-07-19 | — | — | EP | claimed |
| US-4808609-A | Amino-(hydroxy)alkoxy-4-phenylpropyl indoles having antiarrythmic activity | ROUSSEL UCLAF (FR) | 1989-02-28 | — | — | US | claimed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | claimed |
| EP-0142467-B1 | POLYMER COMPOUNDS CONTAINING PIPERIDYL GROUPS AND THEIR USE AS STABILISERS IN SYNTHETIC POLYMERS | CIBA-GEIGY S.p.A. (IT) | 1988-08-24 | — | — | EP | claimed |
| EP-0150139-B1 | INDOLE-ETHYLPHENOL DERIVATIVES, THEIR SALTS, PROCESS FOR THEIR PEPARATION, THEIR USES AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1988-05-18 | — | — | EP | claimed |
| US-4650811-A | HYPOTENSIVE | ROUSSEL UCLAF (FR) | 1987-03-17 | — | — | US | claimed |