⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789435 | 0.89 | NOS1 (0.35) | — | |
| SCHEMBL254648 | 0.88 | GBA1 (0.33) | — | |
| SCHEMBL10700174 | 0.88 | NOS3 (0.32) | — | |
| SCHEMBL3254586 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL459100 | 0.82 | — | — | |
| SCHEMBL8042080 | 0.81 | MAOA (0.31) | — | |
| SCHEMBL8026346 | 0.80 | CHRM1 (0.37) | — | |
| SCHEMBL1461197 | 0.79 | — | — | |
| SCHEMBL1461221 | 0.79 | — | — | |
| SCHEMBL10701436 | 0.79 | SPHK2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794923-A | Benzodioxane compound, and preparation method and application thereof | 南京红云生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-11447489-B2 | Dihydropyrimidinylthiazole for the treatment and prophylaxis of hepatitis B virus infection | HOFFMANN-LA ROCHE INC. (US) | 2022-09-20 | — | — | US | claimed |
| WO-2021238827-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 南京红云生物科技有限公司 | 2021-12-02 | — | — | WO | claimed |
| EP-3732177-B1 | DIHYDROPYRIMIDINYLTHIAZOLE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2021-11-17 | — | — | EP | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| US-20210061801-A1 | DIHYDROPYRIMIDINYLTHIAZOLE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2021-03-04 | — | — | US | claimed |
| EP-3732177-A1 | DIHYDROPYRIMIDINYLTHIAZOLE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2020-11-04 | — | — | EP | claimed |
| CN-111511739-A | Dihydropyrimidinylthiazoles for the treatment and prevention of hepatitis B virus infections | 豪夫迈·罗氏有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-106798740-B | Medicine for treating bacterial infection | 四川省人民医院 | 2020-05-19 | — | — | CN | claimed |
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | claimed |
| EP-0369743-A2 | Heterocyclic amides | ZENECA LIMITED (GB) | 1990-05-23 | — | — | EP | claimed |
| EP-0334148-A2 | Hetaryl-1,10-phenanthroline derivatives | BAYER AG (DE) | 1989-09-27 | — | — | EP | claimed |
| EP-0201400-B1 | 4-PHENYL PROPYL INDOLE DERIVATIVES AND THEIR SALTS, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1989-07-19 | — | — | EP | claimed |
| US-4808609-A | Amino-(hydroxy)alkoxy-4-phenylpropyl indoles having antiarrythmic activity | ROUSSEL UCLAF (FR) | 1989-02-28 | — | — | US | claimed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | claimed |
| EP-0150139-B1 | INDOLE-ETHYLPHENOL DERIVATIVES, THEIR SALTS, PROCESS FOR THEIR PEPARATION, THEIR USES AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1988-05-18 | — | — | EP | claimed |
| US-4650811-A | HYPOTENSIVE | ROUSSEL UCLAF (FR) | 1987-03-17 | — | — | US | claimed |
| US-4279912-A | ANTIALLERGENS, BRONCHODILATORS | ROUSSEL UCLAF (FR) | 1981-07-21 | — | — | US | claimed |
| US-4091115-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1978-05-23 | — | — | US | claimed |