SCHEMBL4591124

SCHEMBL4591124

NCCC12CCCN1CCC2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4590548 0.79 GAA (0.38) CHRNA7KCNH2
SCHEMBL16757065 0.75 KMT2A (0.36) CHRNA7KCNH2
SCHEMBL8968088 0.75 CHRNA7 (0.38) CHRNA7KCNH2
SCHEMBL9561693 0.75 CHRNA7 (0.34) CHRNA7KCNH2
SCHEMBL10924907 0.75 KCNH2 (0.33) CHRNA7KCNH2
SCHEMBL25165704 0.72 KMT2A (0.37) KCNH2
SCHEMBL8265735 0.72 KMT2A (0.37) KCNH2
SCHEMBL30699749 0.72 GAA (0.37)
SCHEMBL10842235 0.71 CHRNA7 (0.33) CHRNA7KCNH2
SCHEMBL24637969 0.71 KCNH2 (0.32) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703233-A2 Process for the preparation of 5-substituted-1-azabicyclo (3.3.0) octanes SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1996-03-27 EP claimed
JP-8041065-A None JP disclosed
JP-6306075-A None JP disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
WO-2022194191-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12D GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) 2022-09-22 WO disclosed
US-20080262031-A1 4-Aminoquinoline Derivatives as Antimalarials CTG PHARMA S.R.L. (IT) 2008-10-23 US disclosed
EP-1846401-B1 NEW 4-AMINOQUINOLINE DERIVATIVES AS ANTIMALARIALS CTG PHARMA S R L (IT) 2008-06-18 EP disclosed
EP-1846401-A1 NEW 4-AMINOQUINOLINE DERIVATIVES AS ANTIMALARIALS CTG Pharma S.r.l. (IT) 2007-10-24 EP disclosed
WO-2006082030-A1 NEW 4-AMINOQUINOLINE DERIVATIVES AS ANTIMALARIALS CTG PHARMA S.R.L. (IT) 2006-08-10 WO disclosed
US-5318977-A New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents G. D. SEARLE & CO. (US) 1994-06-07 US disclosed
US-5280028-A Containing ketone structure in position2 G. D. SEARLE & CO. (US) 1994-01-18 US disclosed
WO-1994000454-A1 BENZIMIDAZOLE COMPOUNDS G.D. SEARLE & CO. (US) 1994-01-06 WO disclosed
EP-0543307-A2 Nootropic agent SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-05-26 EP disclosed
EP-0528026-A1 NEW MESO-AZACYCLIC AROMATIC ACID AMIDES AND ESTERS AS NOVEL SEROTONERGIC AGENTS G.D. SEARLE & CO. (US) 1993-02-24 EP disclosed
EP-0504680-A1 New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents G.D. Searle & Co. (US) 1992-09-23 EP disclosed
WO-1992015590-A1 NEW MESO-AZACYCLIC AROMATIC ACID AMIDES AND ESTERS AS NOVEL SEROTONERGIC AGENTS G.D. SEARLE & CO. (US) 1992-09-17 WO disclosed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 US disclosed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 EP disclosed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CHRNA7 4848/4885KCNH2 4373/4885
US-20080262031-A1 4-Aminoquinoline Derivatives as Antimalarials QTRT1, QTRT2, RECQL CHRNA7 2751/4885KCNH2 1553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.