Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5636397 | 0.79 | MAPT (0.39) | NPC1RAB9ACA12CA9KDM4E | |
| SCHEMBL4591297 | 0.78 | NPC1 (0.44) | NPC1RAB9ACA12CA9HDAC1 | |
| SCHEMBL9727104 | 0.66 | P2RX1 (0.50) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL10396769 | 0.66 | SMN1; SMN2 (0.51) | HDAC1KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL11685836 | 0.66 | MEN1 (0.41) | NPC1RAB9ACA12CA9HDAC1 | |
| SCHEMBL10875014 | 0.65 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2AKCNK3 | |
| SCHEMBL6667710 | 0.64 | RAB9A (0.74) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL3790097 | 0.64 | RAB9A (0.74) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL8804658 | 0.63 | KDM4E (0.82) | NPC1RAB9AKDM4ENPSR1RXFP1 | |
| SCHEMBL13741419 | 0.62 | MEN1 (0.45) | NPC1RAB9ANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176321-B2 | Method for producing 3-amino-4-substituted-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20040204589-A1 | Method for producing 3-amino-4-substituted-5-pyrazolones | FUJIFILM CORPORATION (JP) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204589-A1 | Method for producing 3-amino-4-substituted-5-pyrazolones | KCNH3, KCNH2, KCNJ11 | NPC1 3067/4885RAB9A 585/4885CA12 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.