Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637633 | 0.79 | NPC1 (0.40) | MAPTNPSR1MEN1KMT2ACA12 | |
| SCHEMBL5636009 | 0.74 | MAPT (0.41) | MAPTALDH1A1NPSR1HPGDMEN1 | |
| SCHEMBL4591297 | 0.72 | NPC1 (0.44) | NPSR1MEN1KMT2ACA12CA9 | |
| SCHEMBL14587830 | 0.69 | NPC1 (0.37) | MAPTNPSR1MEN1KMT2AHTT | |
| SCHEMBL9287646 | 0.67 | NOTUM (0.52) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3377974 | 0.64 | RAB9A (0.55) | MAPTALDH1A1MEN1KMT2ALMNA | |
| N-Phenylbenzamide SCHEMBL27770845 | 0.64 | HTT (0.55) | ALDH1A1MEN1KMT2AHTTNPC1 | |
| SCHEMBL10875014 | 0.62 | MEN1 (0.68) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4253031 | 0.61 | RAB9A (0.62) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10396769 | 0.61 | SMN1; SMN2 (0.51) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176321-B2 | Method for producing 3-amino-4-substituted-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20040204589-A1 | Method for producing 3-amino-4-substituted-5-pyrazolones | FUJIFILM CORPORATION (JP) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204589-A1 | Method for producing 3-amino-4-substituted-5-pyrazolones | KCNH3, KCNH2, KCNJ11 | MAPT 4832/4885ALDH1A1 1636/4885NPSR1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.