Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172587 | 0.89 | ALDH1A1 (0.49) | LMNAAOC3ALDH1A1MAPTHTT | |
| SCHEMBL172552 | 0.89 | ALDH1A1 (0.49) | LMNAAOC3ALDH1A1MAPTHTT | |
| SCHEMBL13075028 | 0.89 | ALDH1A1 (0.49) | LMNAAOC3ALDH1A1MAPTHTT | |
| SCHEMBL1295513 | 0.85 | LMNA (0.67) | LMNAAOC3RIPK1ALDH1A1KDM4E | |
| SCHEMBL348229 | 0.85 | LMNA (0.67) | LMNAAOC3RIPK1ALDH1A1KDM4E | |
| SCHEMBL540695 | 0.85 | LMNA (0.67) | LMNAAOC3RIPK1ALDH1A1KDM4E | |
| SCHEMBL28617318 | 0.85 | LMNA (0.67) | LMNAAOC3RIPK1ALDH1A1KDM4E | |
| Phenylpropanol SCHEMBL9863274 | 0.80 | LMNA (0.79) | LMNAAOC3RIPK1ALDH1A1KDM4E | |
| Acetic Acid SCHEMBL29265550 | 0.78 | LMNA (0.57) | LMNAAOC3RIPK1ALDH1A1KDM4E | |
| SCHEMBL21240762 | 0.78 | LMNA (0.52) | LMNAAOC3RIPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966127-A1 | CARBONYL ASYMMETRIC ALKYLATION | Sandoz AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007082771-A1 | CARBONYL ASYMMETRIC ALKYLATION | SANDOZ AG (CH) | 2007-07-26 | — | — | WO | disclosed |