SCHEMBL4591696

SCHEMBL4591696

O=C1C=CC2=C(C1)C(=O)NC2=O

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5690801 0.73
SCHEMBL9187945 0.67 TRPA1 (0.36)
SCHEMBL28650255 0.66
SCHEMBL708902 0.65
SCHEMBL277815 0.64
SCHEMBL10513930 0.64 GSK3A (0.43) GSK3AGSK3B
SCHEMBL9522735 0.64 GSK3A (0.43) GSK3AGSK3B
SCHEMBL30312960 0.62 GSK3A (0.42) GSK3AGSK3B
SCHEMBL9435710 0.62 GSK3A (0.42) GSK3AGSK3B
SCHEMBL31248174 0.61 GSK3A (0.40) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379249-A4 FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION BRISTOL MYERS SQUIBB CO (US) 2008-01-09 EP claimed
EP-1379249-A1 FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION Bristol-Myers Squibb Company (US) 2004-01-14 EP claimed
WO-2002067939-A1 FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION BRISTOL-MYERS SQUIBB COMPANY (US) 2002-09-06 WO claimed
CN-120118047-A Aminothiazole compound and application thereof as brain-permeable histamine H2 receptor agonist 浙江大学 2025-06-10 CN disclosed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed