SCHEMBL4592308

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19157440	0.93	MAPT (0.41)	MAPTCD4ALDH1A1HSD11B1MMP2
	SCHEMBL9906209	0.85	CD4 (0.45)	MAPTCD4ALDH1A1HSD11B1LMNA
	SCHEMBL9906206	0.83	CD4 (0.45)	MAPTCD4ALDH1A1HSD11B1LMNA
	SCHEMBL9540293	0.76	ALDH1A1 (0.49)	MAPTALDH1A1LMNAHSP90AA1KMT2A
	SCHEMBL5557223	0.74	CD4 (0.69)	CD4ALDH1A1LMNAKMT2AHTT
	SCHEMBL4097232	0.73	LMNA (0.51)	MAPTALDH1A1LMNAKMT2ASMN1; SMN2
	SCHEMBL9216667	0.73	CD4 (0.71)	CD4ALDH1A1LMNAKMT2AHTT
	SCHEMBL4092772	0.72	LMNA (0.52)	MAPTALDH1A1LMNAKMT2ASMN1; SMN2
	SCHEMBL9906200	0.70	LMNA (0.52)	MAPTALDH1A1LMNAKMT2ASMN1; SMN2
	SCHEMBL9035999	0.69	CD4 (0.57)	MAPTCD4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.