Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092772 | 0.94 | LMNA (0.52) | ALDH1A1MAPTKMT2ALMNATDP1 | |
| SCHEMBL9906200 | 0.92 | LMNA (0.52) | ALDH1A1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL4097232 | 0.88 | LMNA (0.51) | ALDH1A1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL9906209 | 0.87 | CD4 (0.45) | ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL9273582 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAHTTPOLB | |
| SCHEMBL8192516 | 0.85 | GAA (0.55) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL9906206 | 0.85 | CD4 (0.45) | ALDH1A1MAPTLMNA | |
| SCHEMBL8136774 | 0.82 | L3MBTL1 (0.46) | ALDH1A1MAPTKMT2ALMNAHSP90AA1 | |
| SCHEMBL19157382 | 0.82 | LMNA (0.48) | ALDH1A1MAPTKMT2ALMNATDP1 | |
| SCHEMBL9485554 | 0.78 | KMT2A (0.60) | ALDH1A1KMT2ALMNAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002652-A2 | MODIFIED HAPTENS USEFUL AS IMAGING AND THERAPEUTIC AGENTS | HYBRITECH INCORPORATED (US) | 1993-02-18 | — | — | WO | disclosed |