Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112233 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL15660633 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL29408787 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL67326 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL14508198 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL67324 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL15660631 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL67325 | 0.90 | HIF1A (0.53) | HIF1ALMNAHTTKMT2AATM | |
| SCHEMBL28344253 | 0.85 | HIF1A (0.55) | HIF1ALMNAATM | |
| SCHEMBL28344252 | 0.85 | HIF1A (0.55) | HIF1ALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888535-B1 | NEW HETEROCYCLYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-11-19 | — | — | EP | disclosed |