Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877525 | 0.85 | HRH3 (0.37) | HRH3PDE4BPDE7AF10AKT1 | |
| SCHEMBL221763 | 0.72 | HRH3 (0.39) | HRH3PDE4BPDE7A | |
| Taurine SCHEMBL4592404 | 0.71 | CYP2C19 (0.36) | HRH3F10 | |
| Taurine SCHEMBL4592400 | 0.70 | F10 (0.39) | HRH3F10 | |
| SCHEMBL222300 | 0.68 | HDAC6 (0.34) | HRH3 | |
| SCHEMBL220468 | 0.66 | F10 (0.48) | HRH3F10 | |
| SCHEMBL3885138 | 0.64 | HTR4 (0.33) | HRH3F10 | |
| SCHEMBL9963445 | 0.63 | HRH3 (0.41) | HRH3 | |
| SCHEMBL3874220 | 0.62 | CYP11B2 (0.40) | — | |
| SCHEMBL27316784 | 0.61 | HRH3 (0.42) | HRH3PDE4BPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |