Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340320 | 1.00 | REN (0.35) | RENKMT2ATMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL3272138 | 0.95 | REN (0.35) | RENKMT2ATMEM97SIGMAR1PDE4B | |
| SCHEMBL4582802 | 0.95 | REN (0.35) | RENKMT2ATMEM97SIGMAR1PDE4B | |
| SCHEMBL2338242 | 0.94 | BMP1 (0.35) | RENPDE4BGRM5 | |
| SCHEMBL4592794 | 0.94 | REN (0.34) | RENKMT2ATMEM97SIGMAR1PDE4B | |
| SCHEMBL2334830 | 0.94 | REN (0.34) | RENKMT2ATMEM97SIGMAR1PDE4B | |
| SCHEMBL4592921 | 0.94 | REN (0.34) | RENKMT2ATMEM97SIGMAR1PDE4B | |
| SCHEMBL3268517 | 0.94 | REN (0.34) | RENTMEM97SIGMAR1PDE4BGRM5 | |
| SCHEMBL1037839 | 0.94 | REN (0.36) | RENALDH1A1KDM4EMKNK2GRM5 | |
| SCHEMBL2341326 | 0.93 | REN (0.34) | RENTMEM97SIGMAR1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |