Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331006 | 0.95 | GCGR (0.38) | GCGRKDM4ERAB9AMAPTMEN1 | |
| SCHEMBL2382569 | 0.89 | RAB9A (0.46) | GCGRKDM4ERAB9AMAPTMEN1 | |
| SCHEMBL27697130 | 0.87 | SRC (0.45) | GCGRKDM4ERAB9AMAPTMEN1 | |
| SCHEMBL1513156 | 0.78 | GCGR (0.42) | GCGRKDM4ERAB9AMAPTMEN1 | |
| SCHEMBL10345129 | 0.78 | TLR8 (0.41) | MAPTMEN1ALDH1A1KMT2AHTR2A | |
| SCHEMBL10345132 | 0.76 | TSHR (0.44) | MAPTMEN1ALDH1A1KMT2AHTR2A | |
| SCHEMBL10345139 | 0.76 | TSHR (0.44) | MAPTMEN1ALDH1A1KMT2AHTR2A | |
| SCHEMBL10345217 | 0.76 | TSHR (0.44) | MAPTMEN1ALDH1A1KMT2AHTR2A | |
| SCHEMBL10344837 | 0.76 | TSHR (0.44) | MAPTMEN1ALDH1A1KMT2AHTR2A | |
| SCHEMBL3695485 | 0.76 | TSHR (0.44) | MAPTMEN1ALDH1A1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247418-A1 | NAV1.7 BINDERS | Merck Sharp & Dohme LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109102-A1 | NAV1.7 BINDERS | MERCK SHARP & DOHME CORP. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2015150822-A1 | MATERIALS AND METHODS FOR ANALYSING PHOSPHORYLATION OF A TARGET POLYPEPTIDE | THE UNIVERSITY OF BATH (GB) | 2015-10-08 | — | — | WO | disclosed |
| EP-1999797-A2 | DEVICE INCLUDING SEMICONDUCTOR NANOCRYSTALS AND A LAYER INCLUDING A DOPED ORGANIC MATERIAL AND METHODS | QD Vision, Inc. (US) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007095061-A2 | DEVICE INCLUDING SEMICONDUCTOR NANOCRYSTALS AND A LAYER INCLUDING A DOPED ORGANIC MATERIAL AND METHODS | QD VISION, INC. (US) | 2007-08-23 | — | — | WO | disclosed |