SCHEMBL4592877

SCHEMBL4592877

Nc1cc(C(=O)c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
GAA P10253 1/20 0.53
ADORA1 P30542 1/20 0.50
POLB P06746 1/20 0.50
PDE4A P27815 1/20 0.47
MAPK14 Q16539 2/20 0.47
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PBRM1 Q86U86 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
AKR1C3 P42330 1/20 0.43
ATM Q13315 2/20 0.42
CDC25B P30305 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8033801 0.80 MAPT (0.72) MAPTGAAADORA1POLBMAPK14
SCHEMBL28641260 0.80 MEN1 (0.61) MAPTGAAPOLBALDH1A1LMNA
SCHEMBL9994810 0.79 MAPT (0.56) MAPTGAAADORA1POLBMAPK14
SCHEMBL7901398 0.79 MAPT (0.56) MAPTGAAADORA1POLBPDE4A
SCHEMBL686613 0.79 MAPT (0.60) MAPTGAAADORA1POLBALDH1A1
Hydrochloric Acid SCHEMBL5169493 0.77 MAPT (0.58) MAPTGAAADORA1POLBALDH1A1
SCHEMBL29164143 0.77 ALDH1A1 (0.52) MAPTGAAADORA1PDE4AALDH1A1
SCHEMBL27985225 0.76 MAPT (0.67) MAPTGAAADORA1POLBMAPK14
SCHEMBL27449650 0.76 ALDH1A1 (0.54) MAPTGAAADORA1POLBPDE4A
SCHEMBL28359611 0.75 MAPT (0.44) MAPTGAAADORA1POLBPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0607976-B1 Alignment treating agent for liquid crystal cell NISSAN CHEMICAL IND LTD (JP) 2002-11-13 EP claimed
US-12590208-B2 Thermoplastic resin foam, thermoplastic resin foam sheet, fiber-reinforced resin composite, method for manufacturing thermoplastic resin foam, thermoplastic resin foam molded article, method for manufacturing thermoplastic resin foam molded article, and foamed resin composite SEKISUI KASEI CO., LTD. (JP) 2026-03-31 US disclosed
US-20250346717-A1 FOAMED THERMOPLASTIC RESIN PARTICLES, MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES, FOAMED RESIN COMPOSITE, METHOD FOR PRODUCING FOAMED THERMOPLASTIC RESIN PARTICLES, AND METHOD FOR PRODUCING MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES SEKISUI KASEI CO., LTD. (JP) 2025-11-13 US disclosed
EP-4190533-B1 THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM SHEET, FIBER-REINFORCED RESIN COMPOSITE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM, THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, METHOD FOR MANUFACTURING THERMOPLASTIC RESIN FOAM MOLDED ARTICLE, AND FOAMED RESIN COMPOSITE SEKISUI KASEI CO LTD (JP) 2025-10-01 EP disclosed
EP-4538319-A1 FOAMED THERMOPLASTIC RESIN PARTICLES, MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES, FOAMED RESIN COMPOSITE, METHOD FOR PRODUCING FOAMED THERMOPLASTIC RESIN PARTICLES, AND METHOD FOR PRODUCING MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES Sekisui Kasei Co., Ltd. (JP) 2025-04-16 EP disclosed
CN-114206990-B Fiber-reinforced polyarylene sulfide copolymer composite substrate, method for producing same, and molded article containing same 东丽株式会社 2024-06-21 CN disclosed
CN-117677673-A Polyamic acid composition and polyimide cover comprising same PI尖端素材株式会社 2024-03-08 CN disclosed
CN-117651739-A Polyimide cover PI尖端素材株式会社 2024-03-05 CN disclosed
CN-117642286-A Laminate roll 东洋纺株式会社 2024-03-01 CN disclosed
WO-2023238958-A1 FOAMED THERMOPLASTIC RESIN PARTICLES, MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES, FOAMED RESIN COMPOSITE, METHOD FOR PRODUCING FOAMED THERMOPLASTIC RESIN PARTICLES, AND METHOD FOR PRODUCING MOLDED BODY OF FOAMED THERMOPLASTIC RESIN PARTICLES 積水化成品工業株式会社 2023-12-14 WO disclosed
EP-1215043-B1 Polyester film and magnetic recording medium using the same TORAY INDUSTRIES (JP) 2006-03-22 EP disclosed
US-6783889-B2 FOR USE IN DIGITAL RECORDING TYPE CASSETTE TAPE; QUALITY; FOR HIGH-DENSITY RECORDING, DIMENSIONAL STABILITY TORAY INDUSTRIES, INC. (JP) 2004-08-31 US disclosed
US-20040161620-A1 Flame retardant polyester film and processed product including the same TORAY INDUSTRIES, INC. (JP) 2004-08-19 US disclosed
CN-1517402-A Fire resistance polyester film and processed product using the film ������������ʽ���� 2004-08-04 CN disclosed
EP-1441001-A2 Flame-retardant polyester film and processed product including the same TORAY INDUSTRIES, INC. (JP) 2004-07-28 EP disclosed
US-20020114977-A1 Polyester film and magnetic recording medium using the same TORAY INDUSTRIES, INC. (JP) 2002-08-22 US disclosed
CN-1358624-A Polyester film and recording medium using same TORAY INDUSTRIES (JP) 2002-07-17 CN disclosed
EP-1215043-A1 Polyester film and magnetic recording medium using the same TORAY INDUSTRIES, INC. (JP) 2002-06-19 EP disclosed
CN-1320138-A Biaxially oriented film and magnetic recording medium TORAY INDUSTRIES (JP) 2001-10-31 CN disclosed
EP-1142936-A1 BIAXIALLY ORIENTED FILM AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES, INC. (JP) 2001-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590208-B2 Thermoplastic resin foam, thermoplastic resin foam sheet, fiber-reinforced resin composite, method for manufacturing thermoplastic resin foam, thermoplastic resin foam molded article, method for manufacturing thermoplastic resin foam molded article, and foamed resin composite TAF9, TAF1, TAF11 MAPT 105/4885GAA 2755/4885ADORA1 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.