Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3449413 | 0.90 | MAPT (0.50) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL655621 | 0.84 | GAA (0.59) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL655620 | 0.84 | GAA (0.59) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL702046 | 0.84 | GAA (0.59) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL770810 | 0.78 | MAPT (0.56) | MAPTGAAL3MBTL1ALDH1A1CHRM1 | |
| SCHEMBL13601675 | 0.77 | MAPT (0.70) | MAPTGAAL3MBTL1ALDH1A1THRB | |
| SCHEMBL382565 | 0.77 | GAA (0.68) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL8276261 | 0.76 | GAA (0.43) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL23167854 | 0.76 | GAA (0.69) | MAPTGAAL3MBTL1ALDH1A1NOS3 | |
| SCHEMBL12496523 | 0.76 | MAPT (0.67) | MAPTGAAL3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877404-A2 | NOVEL CYCLIC AMINES | F. Hoffmann-Roche AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |